Lipid Modification: Does low-density lipoprotein cholesterol matter in older people? (Jun-16)

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Cardiovascular disease: Meta-analysis finds that gains in all-cause survival with statin treatment are small (Nov-15)

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Myocardial Infarction: benefits and safety of extended dual antiplatelet therapy (Oct-15)

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Atrial Fibrillation – BRIDGE study finds net clinical benefit in favour of forgoing perioperative anticoagulant bridging (July 2015)

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Cardiovascular disease: IMPROVE-IT published: addition of ezetimibe to simvastatin may modestly improve cardiovascular outcomes (June-15)

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Cardiovascular disease: further evidence that digoxin may be associated with an increased risk of mortality (June-15)

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Cardiovascular: RCT investigates safety and benefits of stopping statins in patients with life-limiting conditions (May-15)

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NPC Archive Item: Modelling study finds no net benefit from aspirin plus clopidogrel versus aspirin alone in people with AF unable to take warfarin

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 30 November 2011 This modelling study used data from the ACTIVE-W and ACTIVE-A studies to allow a comparison of dual therapy with aspirin plus clopidogrel versus aspirin alone in […]

NPC Archive Item: Dronedarone▼ increases the risk of heart failure, stroke and death compared to placebo in people with permanent AF

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 28 November 2011 The PALLAS study found that, in patients with permanent atrial fibrillation (AF) at high risk of vascular events, dronedarone▼ more than doubled the risk of the […]

NPC Archive Item: NICE publishes guidance on ticagrelor▼ for acute coronary syndromes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 11 November 2011 NICE recommends ticagrelor (Brilique▼) in combination with low-dose aspirin for up to 12 months as a treatment option for adults with acute coronary syndromes (ACS), i.e. […]