NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22 April 2010 The ACCORD lipid trial in patients with type 2 diabetes concluded that intensifying lipid modification therapy through combination use of fenofibrate and simvastatin (at a daily […]
Category Archives: Cardiovascular disease
NPC Archive Item: Concomitant use of clopidogrel and PPIs: European Medicines Agency updates warning
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 April 2010 Following an analysis of new data, the European Medicines Agency has recommended an amendment to the existing warning over the concomitant use of clopidogrel and proton-pump […]
NPC Archive Item: April 2010 Drug Safety Update from MHRA/CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 09 April 2010 The MHRA and CHM have published the April edition of Drug Safety Update Highlights include: Updated […]
NPC Archive Item: NICE publishes second ACD on dronedarone▼ for non-permanent atrial fibrillation
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9 April 2010 Preliminary recommendations from NICE restrict the use of dronedarone (Multaq®▼) to a limited group of patients with AF. This group consists of those with non-permanent AF […]
NPC Archive Item: How long should clopidogrel be prescribed for after implantation of drug-eluting stents?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 31 March 2010 An interim analysis of data from two studies suggests no benefit for continuing to use clopidogrel in addition to aspirin for more than 12 months after […]
NPC Archive Item: Disappointing results for cangrelor in patients undergoing PCI
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 29 March 2010 Intravenous cangrelor has failed to show a benefit on the primary end point of a composite of death, myocardial infarction (MI) or ischaemia-driven revascularisation 48 hours […]
NPC Archive Item: NICE: no specific recommendations now on choice of tool for use in CV risk estimation
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 29 March 2010 NICE has reissued its guideline on cardiovascular risk assessment and lipid modification (CG67) removing the recommendation to use a specific method for risk estimation (based on […]
NPC Archive Item: Small local ‘snapshot’ study should not discourage use of low cost statins
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22 March 2010 A study of administrative data from one PCT suggested that practices which tended to use more lower-cost statins had slightly fewer patients with a total cholesterol […]
NPC Archive Item: Which antihypertensive drug to use after a diuretic: an ACE-inhibitor or beta-blocker seems preferable to a calcium channel blocker
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19 March 2010 This case control study of lower CV risk patients found that, compared to the combination of diuretic plus beta-blocker, patients taking diuretic plus calcium channel blocker […]
NPC Archive Item: Variation in blood pressure is an independent risk factor for stroke, but does it affect drug choice in hypertension?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19 March 2010 We know already that having raised blood pressure increases the risk of stroke. Recent studies suggest that variation in blood pressure is also an independent risk […]