NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19 March 2010 This case control study of lower CV risk patients found that, compared to the combination of diuretic plus beta-blocker, patients taking diuretic plus calcium channel blocker […]
Category Archives: Cardiovascular disease
NPC Archive Item: Variation in blood pressure is an independent risk factor for stroke, but does it affect drug choice in hypertension?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19 March 2010 We know already that having raised blood pressure increases the risk of stroke. Recent studies suggest that variation in blood pressure is also an independent risk […]
NPC Archive Item: Statins and risk of diabetes
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 01 March 2010 This meta-analysis found statin therapy was associated with a small increase in the absolute risk of developing diabetes. However, for people in whom statin therapy is […]
NPC Archive Item: One-year follow up data for bivalirudin▼ in patients with high-risk STEMI
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 February 2010 The HORIZONS-AMI trial assessed high-risk patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). One year follow-up data to this study suggest […]
NPC Archive Item: NICE publishes guidance on VTE prevention in adult patients in hospital
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 8 February 2010 NICE has published new guidance which aims to reduce the risk of venous thromboembolism (VTE) in patients admitted to hospital, including day case patients. VTE includes […]
NPC Archive Item: Dabigatran etexilate▼ is as effective as warfarin for the short term management of acute venous thromboembolism
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 3 February 2010 In the RE-COVER trial (n=2,564), dabigatran etexilate▼ 150mg twice daily for six months was found to be as effective as dose-adjusted warfarin in preventing recurrent venous […]
NPC Archive Item: Use of triple antithrombotic therapy increases the risk of bleeding four times post MI
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 January 2010 An observational study found that, in patients with first-time MI, the risk of hospital admission for bleeding was four times higher in those taking triple antithrombotic […]
NPC Archive Item: More data suggest aspirin is ineffective for primary prevention in patients with diabetes
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 January 2010 This meta-analysis found aspirin did not statistically significantly reduce the risk of major CV events, CV mortality or all-cause mortality in people with diabetes and no […]
NPC Archive Item: Apixaban vs. enoxaparin as thromboprophylaxis in knee replacement surgery
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22 January 2010 In a non-inferiority design, ADVANCE-1 found that results for oral apixaban were similar to s.c. LMWH enoxaparin 30 mg twice daily (not non-inferior) for a primary […]
NPC Archive Item: HEAAL suggests that a higher, unlicensed dose of losartan may have some benefits over the standard dose in heart failure
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 January 2010 The HEAAL study compared 50mg and 150mg daily doses of losartan in people with heart failure intolerant of ACE inhibitors. It suggested that the (unlicensed) higher […]