NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 11th June 2009 The MHRA and CHM have published the June edition of Drug Safety Update. This issue gives […]
Category Archives: Cardiovascular disease
NPC Archive Item: Standard dose statins reduce the risk of CHD in patients with familial hypercholesterolaemia
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10th June 2009 This retrospective cohort study found that statins significantly reduced the risk of coronary heart disease (CHD) in patients with familial hypercholesterolaemia (FH), even though they were […]
NPC Archive Item: EMEA statement on possible interaction between clopidogrel and proton pump inhibitors
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4th June 2009 Concomitant use of proton pump inhibitors (PPIs) and clopidogrel is not advisable unless absolutely necessary, the EU Committee for Medicinal products for Human Use (CHMP) and […]
NPC Archive Item: Current practice for monitoring and adjusting blood pressure treatment may be inappropriate
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 3rd June 2009 Two recent studies (Keenan et al 2009 and Law et al 2009) raise important concerns about current practice for routine monitoring of blood pressure. Firstly, using […]
NPC Archive Item: Review of ALLHAT concludes that a thiazide is still a good first choice antihypertensive drug
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th May 2009 Thiazide diuretics are unsurpassed as initial therapy for reduction of cardiovascular (including stroke) and renal risk, a review of ALLHAT has concluded. ALLHAT, still the largest […]
NPC Archive Item: WATCHing and wondering: no clear answers about antithrombotics in heart failure
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th May 2009 The WATCH study compared adjusted dose warfarin, aspirin and clopidogrel in patients with heart failure. The study was underpowered but does not provide strong evidence that […]
NPC Archive Item: NICE publishes guidance on rivaroxaban▼ for prevention of VTE after hip and knee surgery
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 5th May 2009 NICE technology appraisal guidance 170▼ recommends oral rivaroxaban (Xarelto®) as an option for the prevention of venous thromboembolism (VTE) in adults having elective total hip replacement surgery or […]
NPC Archive Item: Is clopidogrel ACTIVE for atrial fibrillation?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 17th April 2009 Clopidogrel plus aspirin reduced the risk of a vascular composite end point compared with aspirin alone in people with AF who were at increased risk of […]
NPC Archive Item: Resources relating to Better Care, Better Value indicators
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9th April 2009 The NHS Institute for Innovation and Improvement has recently released four Better Care, Better Value Indicators (BCBV) relating to prescribing. NPC includes resources which will help […]
NPC Archive Item: The polypill – interesting DOO data, but no POOs yet
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 6th April 2009 The Indian Polycap Study (TIPS), a short term, phase II study, suggests that a combination capsule which includes five active ingredients has similar effects on cardiovascular […]