NPC Archive Item: ARBs as effective as ACE inhibitors in CV risk reduction? — Jury still out.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Effects of angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Results from a large randomised controlled trial (TRANSCEND) question […]

NPC Archive Item: Clopidogrel and aspirin + dipyridamole similarly effective in secondary prevention of stroke

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Sacco RL et al. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. New Engl J Med 2008; 359 (published on line 27th August 2008) This study has a […]

NPC Archive Item: Rivaroxaban for prevention of venous thromboembolism in patients undergoing total hip or knee replacement

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Eriksson BI, Borris LC, Friedman RJ et al. Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty. N Engl J Med 2008; 358:2765-75 Kakkar AK, Brenner B, Dahl OE […]

NPC Archive Item: QRISK2 – a valid tool for predicting cardiovascular risk?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Hippisley-Cox J, Coupland C, Vinogradova Y, et al. Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2. BMJ 2008;336;1475–82 QRISK2 may provide a more accurate […]

NPC Archive Item: NICE highlights NPC patient decision aid in its lipid guidance

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. NICE Clinical Guideline 67: Cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease Patients should be given information about their […]

NPC Archive Item: NICE publishes guidance on CV risk assessment and lipid modification

NPC Archive Item: Reducing blood pressure is beneficial in people with hypertension regardless of age

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Blood Pressure Lowering Treatment Trialists’ Collaboration. Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. BMJ 2008; […]

NPC Archive Item: MHRA issue drug alert for Clexane®

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Medicines and Healthcare products Regulatory Agency (MHRA) have issued advice to healthcare professionals about heparin enoxaparin sodium (Clexane®) pre-filled syringes. The manufacturer of this low molecular weight heparin […]

NPC Archive Item: Treating hypertension in the elderly reduces mortality

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Becket NS, Peters R, Fletcher AE, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008;358. Published 31st March 2008 (10.1056/NEJMoa0801369) […]

NPC Archive Item: No benefit from rosuvastatin in heart failure

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Kjekshus J et al. Rosuvastatin in older patients with systolic heart failure. NEJM 2007; 357: 2248-61 (CORONA study) In this study in people with moderate to severe heart failure, […]