NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Servier has announced that their branded versions of perindopril erbumine, (Coversyl® and Coversyl Plus®), also known as perindopril tert-butylamine, have been discontinued and replaced with a different salt called […]
Category Archives: Cardiovascular disease
NPC Archive Item: ACE-I plus ARB misses the target
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The ONTARGET investigators. Telmisartan, ramipril or both in patients at high risk for vascular events. New Engl J Med 2008; 358; 1547-59 What is the background to this? ACE-inhibitors […]
NPC Archive Item: What does ENHANCE tell us about the place in therapy of ezetimibe▼?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Kastelein JJP et al. Simvastatin with or without ezetimibe in familial hypercholesterolaemia. New Engl J Med 2008; 358: 1431-1443 (The ENHANCE study 3rd April 2008) The short answer to […]
NPC Archive Item: NPC Podcast – 15th April 2008
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 3 new studies on CV disease that have received a lot of media attention but SHOULDNT change our practice – ENHANCE (ezetimibe); CORONA (rosuvastatin); ONTARGET (ACE/ARBs) [podcast]http://www.npc.nhs.uk/podcast/NPCiPodcast_15thApril08.mp3[/podcast] Subscribe to […]
NPC Archive Item: Digoxin may increase mortality in atrial fibrillation
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Gjesdal K, Feyzi J, Olsson SB. Digitalis: a dangerous drug in atrial fibrillation? An analysis of the SPORTIF III and V data. Heart 2008;94:191–6 What is the background to […]
NPC Archive Item: Informing smokers about their lung age may help them to stop smoking
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Parkes G, Greenhalgh T, Griffin M, et al. Effect on smoking quit rate of telling patients their lung age : the Step2quit randomised controlled trial. BMJ Online first doi:10.1136/bmj.39503.582396.25 (published […]
NPC Archive Item: Do approval requirements restricting access to clopidogrel after stenting have adverse effects on patients?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Sheehy O et al. Restrictive access to clopidogrel and mortality following coronary stent implantation. CMAJ 2008;178(4):413-20 What is the background to this? Clopidogrel can be used in combination with […]
NPC Archive Item: Ezetimibe▼ doesn’t ENHANCE statins
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. What is this about? The results (login required) of the ENHANCE Study have found no significant difference between the combination of ezetimibe▼ and simvastatin compared to simvastatin alone in […]
NPC Archive Item: Is QRISK a better way to assess cardiovascular risk?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Hippisley-Cox J, et al. Performance of the QRISK cardiovascular risk prediction algorithm in an independent UK sample of patients from general practice: a validation study. Heart 2008; 94: 34-39. […]
NPC Archive Item: Stopping clopidogrel may be associated with an increased risk of death and MI
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Ho PM, Petersen ED, Wang L, et al. Incidence of death and acute myocardial infarction associated with stopping clopidogrel after acute coronary syndrome. JAMA 2008:299;532–9 What is the background […]