NPC Archive Item: Intensive glucose control in type 2 diabetes: conclusions unchanged

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 3rd August 2009 A meta-analysis of prospective randomised controlled trials suggests a small benefit of intensive glucose control in people with type 2 diabetes in reducing the risk of […]

NPC Archive Item: Latest data on saxagliptin

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th July 2009, A phase III, 24 week randomised controlled trial has assessed the efficacy and short-term safety of saxagliptin 2.5, 5 and 10mg versus placebo as add-on therapy […]

NPC Archive Item: Early revascularisation offers little over intensive medical therapy in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 21st July 2009 This large trial found no benefit in rates of survival or major vascular events from early versus later revascularisation in people with type 2 diabetes and […]

NPC Archive Item: Insulin glargine and possible cancer link

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 9th July 2009 New data show that insulin glargine is not associated with an increase in cancer (07/08/12) Since these materials were published, ORIGIN (2012), a 6-year randomised controlled […]

NPC Archive Item: Does the LEAD-6 trial clarify the role of liraglutide▼ vs. exenatide▼ in type 2 diabetes?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24th June 2009, updated 16th July 2009 (action and what is the background to this) The open-label LEAD-6 study compared once daily liraglutide▼ to twice daily exenatide▼ in 264 […]

NPC Archive Item: RECORD study confirms heart failure and fracture risks of rosiglitazone: uncertainties remain over other CV risks

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15th June 2009 The authors of this non-inferiority study claim non-inferiority of dual therapy with rosiglitazone plus metformin or a sulfonylurea compared to dual therapy with metformin plus a […]

NPC Archive Item: HbA1c to be reported in different units from June 1st 2009.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10th June 2009 From 1st June 2009, glycated haemoglobin (HbA1c) in all people with diabetes will be measured in millimoles per mol (mmol/mol) as well as by percentage (%), […]

NPC Archive Item: NICE updates guidance on management of type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 8th June 2009 NICE clinical guideline 87 partially updates recommendations for the management of type 2 diabetes, with specific new recommendations about blood glucose control with sitagliptin▼, vildagliptin▼, pioglitazone▼, […]

NPC Archive Item: Intensive glucose control in type 2 diabetes: what part does it play?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 1st June 2009 A meta-analysis of prospective randomised controlled trials suggests a small benefit of intensive glucose control in people with type 2 diabetes in reducing coronary heart disease […]

NPC Archive Item: Another call to re-evaluate the emphasis given to tight control of blood glucose in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th April 2009 Many experienced clinicians are calling for a change in emphasis in care for patients with type 2 diabetes. Authors in a recent review express a similar […]