NPC Archive Item: RECORD study confirms heart failure and fracture risks of rosiglitazone: uncertainties remain over other CV risks

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15th June 2009 The authors of this non-inferiority study claim non-inferiority of dual therapy with rosiglitazone plus metformin or a sulfonylurea compared to dual therapy with metformin plus a […]

NPC Archive Item: HbA1c to be reported in different units from June 1st 2009.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10th June 2009 From 1st June 2009, glycated haemoglobin (HbA1c) in all people with diabetes will be measured in millimoles per mol (mmol/mol) as well as by percentage (%), […]

NPC Archive Item: NICE updates guidance on management of type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 8th June 2009 NICE clinical guideline 87 partially updates recommendations for the management of type 2 diabetes, with specific new recommendations about blood glucose control with sitagliptin▼, vildagliptin▼, pioglitazone▼, […]

NPC Archive Item: Intensive glucose control in type 2 diabetes: what part does it play?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 1st June 2009 A meta-analysis of prospective randomised controlled trials suggests a small benefit of intensive glucose control in people with type 2 diabetes in reducing coronary heart disease […]

NPC Archive Item: Another call to re-evaluate the emphasis given to tight control of blood glucose in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th April 2009 Many experienced clinicians are calling for a change in emphasis in care for patients with type 2 diabetes. Authors in a recent review express a similar […]

NPC Archive Item: Severe hypoglycaemia may increase the risk of dementia in elderly patients with type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22nd April 2009 A study has found that episodes of severe hypoglycaemia requiring hospital treatment were associated with an increased risk of dementia. This cohort study involved elderly patients […]

NPC Archive Item: Newer insulins have only limited clinical benefits

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23rd March 2009 A Canadian Heath Technology Assessment has concluded that the newer, insulin analogues offer little clinical advantage over older, conventional insulins in terms of glycaemic control or […]

NPC Archive Item: BMJ editorial criticises new QoF target for diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23rd March 2009 An editorial in the BMJ concludes that there should be a re-evaluation of recommendations about what constitutes high quality care for older people with type 2 […]

NPC Archive Item: Incretin-based therapies in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24th February 2009 Madsbad S. Treatment of type 2 diabetes with incretin-based therapies. The Lancet 2009; 373:438-39 Incretin-based therapies may offer a new option in the treatment of type […]

NPC Archive Item: Once again, intensive glucose control does not benefit people with established type 2 diabetes if other cardiovascular risk factors are addressed

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The VADT study found that tight control of blood glucose did not reduce the risk of major cardiovascular events, microvascular complications, or death in people with type 2 diabetes […]