Category Archives: Diabetes

NPC Archive Item: Newer insulins have only limited clinical benefits

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23rd March 2009 A Canadian Heath Technology Assessment has concluded that the newer, insulin analogues offer little clinical advantage over older, conventional insulins in terms of glycaemic control or […]

NPC Archive Item: BMJ editorial criticises new QoF target for diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23rd March 2009 An editorial in the BMJ concludes that there should be a re-evaluation of recommendations about what constitutes high quality care for older people with type 2 […]

NPC Archive Item: Incretin-based therapies in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24th February 2009 Madsbad S. Treatment of type 2 diabetes with incretin-based therapies. The Lancet 2009; 373:438-39 Incretin-based therapies may offer a new option in the treatment of type […]

NPC Archive Item: Once again, intensive glucose control does not benefit people with established type 2 diabetes if other cardiovascular risk factors are addressed

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The VADT study found that tight control of blood glucose did not reduce the risk of major cardiovascular events, microvascular complications, or death in people with type 2 diabetes […]

NPC Archive Item: Glitazones double the risk of bone fracture in women

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. A well-conducted meta-analysis has found that rosiglitazone and pioglitazone▼ approximately double the risk of fractures in women, but not men. Action Health professionals should heed MHRA warnings and follow […]

NPC Archive Item: Liraglutide plus metformin data from the LEAD-2 Met trial

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Nauck M, Frid A, Hermansen K et al. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes mellitus (LEAD-2 Met). […]

NPC Archive Item: Aspirin ineffective for primary prevention in patients with diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Belch J, MacCuish A, Campbell I, et al. The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in […]

NPC Archive Item: Once weekly vs twice daily exenatide▼ in the DURATION-1 trial

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Drucker DJ, Buse JB, Taylor K et al for the DURATION-1 Study Group. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, […]