NPC Archive Item: Fenofibrate in type 2 diabetes – reduces need for laser eye treatment, but no effect on visual acuity (or coronary event rate or mortality)

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Keech AC et al. Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial Lancet 2007, published online 6th November DOI:10.1016/S0140-6736(07)61607-9 […]

NPC Archive Item: Fibrates not first choice drugs for most patients, say MHRA and CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Fibrates should not be used as first line lipid-lowering drugs for primary or secondary prevention of cardiovascular disease. So say the MHRA and CHM in the most recent issue […]

NPC Archive Item: Vildagliptin launch delayed

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The European launch of vildagliptin (Glavus®) has been delayed by a safety update according to PharmaTimes. Pooled safety data shows more frequent liver enzyme elevations with the 100mg once daily […]

NPC Archive Item: Diabetes news – safety review of glitazones; inhaled insulin discontinued.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Medicines and Healthcare products Regulatory Agency have announced the outcome of a Europe wide safety review of the glitazones. The review found a positive benefit-risk balance for both […]

NPC Archive Item: Better HbA1c control with biphasic or prandial insulin than basal insulin in type 2 diabetes, but more weight gain and hypoglycaemia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Holman R et al. Addition of biphasic, prandial or basal insulin to oral therapy in type 2 diabetes. N Engl J Med 2007; 357. Published on line on September […]

NPC Archive Item: Lowering blood pressure saves lives in people with type 2 diabetes – the ADVANCE study.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. What does this study claim? The Lancet published the results of the ADVANCE study on the 2nd September 2007. It examined the effect of a fixed combination of an […]