NPC Archive Item: More evidence for self-monitoring of blood glucose in type 2 diabetes?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22nd February 2011 A study has found that a structured self-monitoring of blood glucose intervention package improved glycaemic control compared with enhanced usual care in patients with poorly controlled type […]

NPC Archive Item: Is pioglitazone▼ associated with an increased cardiovascular risk similar to rosiglitazone?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 16 December 2010 Rosiglitazone was withdrawn from clinical use across Europe because of concerns over excess cardiovascular (CV) risk. This cohort study found that pioglitazone▼ was associated with the […]

NPC Archive Item: NICE guidance on liraglutide▼ for type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 11 November 2010 NICE has issued guidance on the use of liraglutide▼ for the treatment of type 2 diabetes. Liraglutide 1.2mg is a dual therapy option only in very limited […]

NPC Archive Item: Does intensive blood glucose control reduce microvascular outcomes in type 2 diabetes? Results from ACCORD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 21 October 2010 An analysis of the ACCORD study has found that intensive blood glucose control did not reduce composite advanced microvascular outcomes (renal complications, eye complications or peripheral […]

NPC Archive Item: Rosiglitazone: withdrawal from clinical use

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24 September 2010 Suspension of marketing authorisations for rosiglitazone (Avandia® and the combination product with metformin, Avandamet®) has been recommended by the European Medicines Agency (EMA), following concerns over excess […]

NPC Archive Item: Are higher doses of insulin glargine associated with cancer?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 13 July 2010 New data show that insulin glargine is not associated with an increase in cancer (07/08/12) Since these materials were published, ORIGIN (2012), a 6-year randomised controlled trial, has […]

NPC Archive Item: A key message on intensive blood-pressure control in type 2 diabetes mellitus from ACCORD

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 20 April 2010 The ACCORD blood-pressure (BP) study conducted in patients with type 2 diabetes at high risk for cardiovascular (CV) disease concluded that intensive BP control to a target […]

NPC Archive Item: Fenofibrate does not reduce CV events in patients with type 2 diabetes when added to simvastatin

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 22 April 2010 The ACCORD lipid trial in patients with type 2 diabetes concluded that intensifying lipid modification therapy through combination use of fenofibrate and simvastatin (at a daily […]

NPC Archive Item: Insulin use may increase mortality in type 2 diabetes

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 15 April 2010 A large observational study found a statistically significant association between all-cause mortality and exposure to insulin in people with type 2 diabetes, with nearly a three times […]

NPC Archive Item: Update on glitazones and cardiovascular risks

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 19 March 2010 In a recent Science Advisory, the American Heart Association and the American College of Cardiology Foundation have summarised the currently available data on the cardiovascular risks […]