Study suggests psychotropic drugs may be overprescribed for people with intellectual disability (Oct-15)

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Intracranial haemorrhage: risk increased with concurrent use of antidepressants and non-steroidal anti-inflammatory drugs (Sep-15)

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Antipsychotics: more data on the risk of death in people with dementia (May-15)

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NPC Archive Item: Continuing donepezil treatment in patients with moderate-to-severe Alzheimer’s disease

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 20th March 2012 In a relatively small (n=295) randomised controlled trial of moderate-to-severe Alzheimer’s disease, continuing donepezil resulted in slower cognitive decline over 12 months than stopping donepezil. However, […]

NPC Archive Item: A comparison of the effectiveness of antimanic drugs in acute mania

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 November 2011 A systematic review and multiple-treatment meta-analysis suggests that antipsychotic drugs are significantly more effective than mood stabilisers in the acute treatment of manic episodes in adults. […]

NPC Archive Item: Scottish Medicines Consortium accepts use of paliperidone palmitate▼ injection for schizophrenia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 14 November 2011 Following a re-submission by the manufacturer, the Scottish Medicines Consortium (SMC) has accepted paliperidone palmitate▼ prolonged-release injection for use within NHS Scotland for specific adult patients* […]

NPC Archive Item: Treating pain to reduce behavioural disturbances in people with dementia

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2 August 2011 A randomised controlled trial suggests that a systematic approach to the management of pain in people with dementia reduces agitation and may reduce the number of […]

NPC Archive Item: New NICE guideline on common mental health disorders: identification and pathways to care

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 16 June 2011 The new NICE clinical guideline 123 focuses on improving access to services for people with common mental health disorders. This involves improving identification and recognition of […]

NPC Archive Item: Antidepressants are effective for people with depression and chronic physical health problems

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 4th May 2011 A systematic review concluded that selective serotonin reuptake inhibitors (SSRIs, e.g. sertraline or citalopram) are probably the antidepressants of first choice in people with depression and chronic […]

NPC Archive Item: NICE reviews its guidance on drug treatment of Alzheimer’s disease

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 28 April 2011 A NICE review and re-appraisal of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s disease has resulted in a change in the guidance. Specifically: […]