NPC Archive Item: May Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 26 May 2010 The MHRA and CHM have published the May edition of Drug Safety Update This edition includes […]

NPC Archive Item: April 2010 Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 09 April 2010 The MHRA and CHM have published the April edition of Drug Safety Update Highlights include: Updated […]

NPC Archive Item: Cladribine – another potential new oral treatment for MS?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23 March 2010 Oral cladribine, given as one of two cumulative doses (either 3.5mg or 5.25mg/kg) in short courses, was more effective at preventing relapse than placebo in the […]

NPC Archive Item: Fingolimod – a potential new oral treatment for multiple sclerosis?

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23 March 2010 Data from the 24 month FREEDOMS trial has shown that fingolimod, a once daily, oral drug for the treatment of relapsing-remitting multiple sclerosis (RRMS), was more […]

NPC Archive Item: Report considers hospital prescribing of ‘NICE appraised’ and ‘low cost’ medicines.

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 30 November 2009 The NHS Information Centre has issued a report considering expenditure on medicines in hospitals in England in 2008. It includes a table focusing on medicines positively […]

NPC Archive Item: Silver dressings are no more effective than unmedicated low-adherence dressings for treating leg ulcers

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 11 November 2009 The VULCAN study found no evidence to support the use of silver dressings under compression bandaging for the treatment of venous leg ulcers. Compared with non-silver […]

NPC Archive Item: Everolimus▼ for advanced renal cell cancer after VEGF-inhibitors have failed

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2nd October 2009, The phase III RECORD-1 study compared oral everolimus to placebo in 410 patients with metastatic renal cell carcinoma whose disease had progressed despite treatment. The trial […]

NPC Archive Item: Gefitinib▼ for locally advanced or metastatic non-small-cell lung cancer

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24th August 2009, Gefitinib▼ is licensed for use in patients with locally advanced or metastatic non-small-cell lung cancer with activating mutations of the epidermal growth factor receptor tyrosine kinase. […]

NPC Archive Item: Overdiagnosis in breast cancer screening

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 30th July 2009 A systematic review of published trends in the incidence of breast cancer, before and after introduction of mammography screening, identifies that one in every three breast […]

NPC Archive Item: July Drug Safety Update from MHRA/CHM

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 7th July 2009 The MHRA and CHM have published the July edition of Drug Safety Update. This issue gives […]