NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. FDA advises that the manufacturers of the tumour necrosis factor alpha (TNF-α) inhibitors, adalimumab▼, etanercept▼, infliximab▼, and certolizumab* must strengthen existing warnings to highlight the risk of potentially fatal […]
Category Archives: Other therapeutics
NPC Archive Item: Seeding trials – marketing framed as science
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Hill KP et al. The ADVANTAGE seeding trial: a review of internal documents. Ann Intern Med 2008; 149: 251-258 Evidence suggests that some clinical trials may have more to […]
NPC Archive Item: September Drug Safety Update from MHRA/CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 9th September 2008 The MHRA and CHM have published the September edition of Drug Safety Update. Included in this […]
NPC Archive Item: Alitretinoin for severe, refractory chronic hand eczema
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Ruzicka T, Lynde CW, Jemec GBE et al. Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results […]
NPC Archive Item: August Drug Safety Update from MHRA/CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 8th August 2008 The MHRA and CHM have published the August edition of Drug Safety Update. In this issue […]
NPC Archive Item: July Drug Safety Update from MHRA/CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 11th July 2008 The MHRA and CHM have published the latest issue of Drug Safety Update (7th July 2008). […]
NPC Archive Item: EMEA issues new warning for etoricoxib▼, epoetins and ergot-derived dopamine agonists
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Following reviews of the risks and benefits of several drugs, the European Medicines Agency (EMEA) has recommended that: warnings and contraindications should be strengthened for etoricoxib▼ for the treatment […]
NPC Archive Item: CKS updates guidance on the treatment of nausea and vomiting in pregnancy
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. In the absence of any good-quality clinical evidence in this area, this updated guidance from CKS provides pragmatic advice for the management of women with nausea and vomiting in […]
NPC Archive Item: Company trial data reports may be misleading
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Concerns have once again been raised about the manipulation of clinical trials and reviews and the misrepresentation of data by pharmaceutical companies and researchers. A recent JAMA editorial suggests […]
NPC Archive Item: Sequential therapy may improve eradication rates for H pylori
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. Jafri NS, Hornung CA, Howden CW. Meta-analysis: Sequential therapy appears superior to standard therapy for Helicobacter pylori infection in patients naïve to treatment. Ann Intern Med 2008; 148 published […]