Rapid Update 1- June 2018: Opioids: interventions to reduce use in chronic non-cancer pain

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Rapid Update 2- December 2017: Gabapentin and opioids: Observational study finds increased risk of opioid-related death when used in combination

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Rapid Update 3- September 2017: Osteoarthritis: systematic review and individual patient data meta-analysis finds no good evidence to support the use of glucosamine

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Rapid Update 2- June 2017: NSAIDs and risk of acute myocardial infarction

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Rapid Update 1 – April 2017: Pain: meta-analysis finds limited efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) for spinal pain

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Rapid Update 3 – December 2016: Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis

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Network meta-analysis finds significant differences between types of placebo and improvements in pain score (Nov-15)

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NPC Archive Item: Even more data on cardiovascular risks of NSAIDs: time to review prescribing

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 10 October 2011 A meta-analysis of observational studies has added to the evidence base confirming an increased risk of cardiovascular (CV) events with coxibs and traditional NSAIDs. The study […]

NPC Archive Item: Scottish Medicines Consortium accepts restricted use of tapentadol▼ prolonged-release tablets for severe chronic pain in adults

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 02 September 2011 After a re-submission by the manufacturer, the Scottish Medicines Consortium (SMC) has accepted tapentadol▼ prolonged-release (Palexia® SR) tablets for restricted use within NHS Scotland, for the […]

NPC Archive Item: MHRA Drug Safety Update August 2011

NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 15 August 2011 The August 2011 edition of Drug Safety Update (DSU) highlights that use of pioglitazone▼ is associated […]