NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24 June 2011 The MHRA has updated current advice on dosing for children’s liquid medicines containing paracetamol. The updated dosing has a larger number of narrower age bands, and […]
Category Archives: Pain
NPC Archive Item: Cochrane review supports the use of paracetamol in acute migraine
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 16th February 2011 A Cochrane review of 10 studies with over 2,700 patients, found that a single oral dose of paracetamol 1000mg was effective in relieving moderate to severe […]
NPC Archive Item: January drug safety update: risk of heart failure when pioglitazone is used with insulin
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 20th January 2011 The MHRA and CHM have published the January edition of Drug Safety Update This edition advises […]
NPC Archive Item: Opioid analgesics associated with an increased risk of adverse events compared with NSAIDs
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 14th January 2011 An observational study has found that, in older adults with arthritis, use of opioid analgesics was associated with an increased risk of morbidity and mortality, compared […]
NPC Archive Item: Less anaemia with celecoxib vs diclofenac plus PPI, but no difference in GI complications (and don’t forget CV risks)
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 6 July 2010a The CONDOR study found a lower risk of anaemia, mainly of presumed occult GI origin, with celecoxib compared to diclofenac plus PPI. However, rates of GI haemorrhage, […]
NPC Archive Item: NICE publishes clinical guideline on neuropathic pain
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2 June 2010 NICE has published a new clinical guideline on the pharmacological management of neuropathic pain in adults in non-specialist settings (CG96). This updates and replaces recommendations on the […]
NPC Archive Item: EMEA recommends withdrawal of co-proxamol
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 2nd July 2009 The EMEA has recommended that the marketing authorisations for dextropropoxyphene-containing medicines are withdrawn across the European Union (EU) because their benefits do not outweigh their risks. […]
NPC Archive Item: Combination therapy with DMARDs is BeSt
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 5th February 2009 Four different DMARD treatment strategies in people with recent onset rheumatoid arthritis significantly improved patient-orientated outcomes after two years. Earlier improvements were seen in those initially […]
NPC Archive Item: NICE publishes clinical guidance on management of rheumatoid arthritis
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 27th February 2009 The NICE guideline (CG79) covers the management of rheumatoid arthritis (RA) of recent onset and more established disease. It includes sections on diagnosis and referral, pharmacological […]
NPC Archive Item: All non-analgesic drug classes are similarly effective in the treatment of neuropathic pain
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 26th January 2009 A Canadian Health Technology Assessment concludes that, in patients with neuropathic pain, there is no statistically significant difference in clinical response rates between tricyclic antidepressants, anticonvulsants […]