NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 24 August 2011 Following a review of safety data, the US FDA has restricted the use of simvastatin▼* 80 mg to reduce the risk of muscle damage (myopathy). The […]
Category Archives: Patient safety and risk
NPC Archive Item: FDA concludes that A2RAs don’t increase the risk of cancer
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 20 July 2011 An FDA meta-analysis of 31 randomised controlled trials found that treatment with an angiotensin-2 receptor antagonist (A2RA) does not increase the risk of cancer. Level of […]
NPC Archive Item: An improved organisational culture can support performance in healthcare
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 5 July 2011 Summary Organisational culture matters when introducing change and in achieving high performance in healthcare. Some of the reasons why organisations may struggle to deliver change are: […]
NPC Archive Item: Olmesartan reduces disease oriented outcomes but may have potential cardiovascular safety concerns
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 28th March 2011 The ROADMAP trial found olmesartan delayed the onset of microalbuminuria in patients with type 2 diabetes and normoalbuminuria. While this disease-oriented outcome (DOO) suggested a potential benefit […]
NPC Archive Item: Observational study suggests candesartan may be preferable to losartan in heart failure
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 20th January 2011 A Swedish observational study has suggested that patients with heart failure have improved survival when they are treated with candesartan compared with losartan. This study has […]
NPC Archive Item: NPSA patient safety alert on lithium; potential for significant numbers of NHS organisations to be non-compliant with December 2010 deadline
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 13 December 2010 The National Patient Safety Agency (NPSA) receives more than 100 adverse reports a year relating to lithium. Errors include failure to monitor serum levels and adjust dose levels […]
NPC Archive Item: Reducing treatment dose errors with low molecular weight heparins
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 06 September 2010 Introduction In July 2010, the National Patient Safety Agency (NPSA) issued its Rapid Response Report: Reducing treatment dose errors with low molecular weight heparins (LMWHs)1, making […]
NPC Archive Item: Calcium supplements without vitamin D may increase the risk of MI
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 23rd August 2010 This meta-analysis found that calcium supplements without vitamin D increased the risk of myocardial infarction (MI) versus control by about 30% in relative terms, but did not […]
NPC Archive Item: May Drug Safety Update from MHRA/CHM
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. The Drug Safety Update is an NHS Evidence accredited provider 26 May 2010 The MHRA and CHM have published the May edition of Drug Safety Update This edition includes […]
NPC Archive Item: What is the place in therapy of simvastatin 80mg in the light of recent MHRA guidance?
NOTE – This is an archive post from the NPC and has not been updated since first publication. Therefore, some hyperlinks may no longer be working. 25 May 2010 The May edition of Drug Safety Update includes an article advising healthcare professionals that the product information for simvastatin has been updated to highlight the increased […]